Simon Hopkinson grew up in England. He acted as a child at the Mermaid Theatre, and won the Dobell Drama Award for his first play 'No Obligation', which he wrote at the age of seventeen. After working at several theatres in England and Scotland as a stage manager, Hopkinson emigrated to Victoria in 1970. There, he became production manager at the Melbourne Theatre Company. In the following year, he established the Melbourne Theatre Company Youth Theatre. He has served as a board member of several theatres, tutored in drama and been the co-artistic director of the Darwin Theatre Group.
The author and director of numerous plays (many of which are unpublished) Hopkinson has also written scripts for the television programme Bananas in Pyjamas, and numerous related children's books. Several of his children's books have been translated into other languages.