Drusilla Modjeska was born in England, but, after spending some time in New Guinea during the 1960s, she has lived in Australia since 1971. After studying at the Australian National University, Modjeska completed her education at the University of New South Wales, writing a PhD thesis on women writers of the 1920s and 1930s. This was revised and expanded for the influential book, Exiles at Home: Australian Women Writers 1925-1945 (1981), establishing Modjeska as a prominent voice in Australian literary studies. She has since worked at a number of institutions, including the University of Technology, Sydney, and the University of New South Wales. She has also edited a number of collections of non-fiction and fiction.
Modjeska has been a regular reviewer for several newspapers and magazines, and, since 1990, has published a number of widely-admired biographical and creative works. Her biography of her mother, Poppy (1990), won a number of prizes, including the Douglas Stewart Prize for non-fiction. She also contributed a novella to Secrets (1995), a collaboration with Robert Dessaix (q.v.) and Amanda Lohrey (q.v.). Modjeska's most recent work is Stravinsky's Lunch (2000) which recounts the lives of Australian artists Grace Cossington Smith (1893-1947) and Stella Bowen (1892-1984).
Drusilla Modjeska won a three year Senior ARC Research Fellowship in 2000 to complete a study on 'Post-Colonialism and Life-Writing in New Guinea after 1966' at the University of Sydney: she spent some years in Papua New Guinea in the early years of her marriage to anthropologist Nicholas Mojeska, including studying at the University of Papua New Guinea. She remains committed to supporting literacy and education in remote Papua New Guinean communities. She has also taught at the University of Technology, Sydney, where she was part of the team that established the writing program.