Jesse Blackadder graduated from the New South Wales Institute of Technology with a bachelor of arts in Communications, majoring in film and writing. She later received a Doctor of Creative Arts from the University of Western Sydney. She also held a Master of Applied Science (Social Ecology), also from the University of Western Sydney.
Blackadder publishing her first novel for adults in 2005: After the Party. It was followed by historical novel The Raven's Heart (2011), a story of Mary, Queen of Scots. Her third novel, Chasing the Light : A Novel of Antarctica, was funded by an Antarctic Arts Fellowship. Blackadder also published a range of children's books, focusing on Australian animals such as koalas and flying foxes, as well as influential introduced species, including brumbies. One work, Stay : The Last Dog in Antarctica, was also influenced by her Antarctic Arts Fellowship.
Blackadder's novel Sixty Seconds (2017) explores the devastating aftermath of a backyard tragedy.
From 2016, Blackadder branched out into screen-writing, with writers' room placements on Mustangs FC (Matchbox Pictures) and Seven Little Australians (Every Cloud Productions). With eleven other women, she was selected as part of The Athena Project, an initiative to develop the careers of women scriptwriters, funded by Screen Australia's Gender Matters: Brilliant Careers program.
Blackadder had been the student representative for the Association of the Study of Literature, the Environment, and Culture - Australia and New Zealand. She was a member of the Byron Writers Festival board and founder of the festival's StoryBoard, a mobile creative program for young people.
Jesse Blackadder died in June 2020, after a battle with cancer.