Pamela Rushby grew up and was educated in Ipswich, Queensland, apart from a period spent in Penang, Malaysia. She worked as an advertising copywriter, a publicity officer and a pre-school teacher. Rushby studied ancient history, journalism, art history, and writing and producing for television. As technology changed, she also wrote and produced multimedia texts.
In 1993, Rushby was awarded a Writers' Project Grant from the Literature Board of the Australia Council to travel to Egypt and Jordan and work on archaeological excavations to research a children's novel. She retains her interest in the area and its history, being shortlisted for the Text Prize in 2018 for an historical children's novel on the practice of mummy parties. She won a Churchill Fellowship in 1994 to travel to Canada and study educational television at TVOntario. In 2006, she received the May Gibbs Children's Literature Trust Fellowship.
The author of three dozen children's books, picture books, and plays, she has won the Davitt Award and the Ethel Turner Prize (NSW Premier's Literary Awards) and been shortlisted for many more, with particular success for her 2014 novel The Ratcatcher's Daughter.
She is the mother of Allison Rushby.