Born in the Blue Mountains to radio comedian parents, David Manning Foster studied Science at the University of Sydney, graduating in 1967 with the University Medal for Chemistry. Three years later he received his doctorate in inorganic chemistry from the Australian National University, and spent a year as a Fellow of the National Institute of Health in the United States in 1970. Foster then worked as a senior research scientist at the Department of Medicine, University of Sydney, 1971-1972, before retiring to begin writing full-time. He has also worked as a truck driver, postal worker, labourer, prawn trawler crewman, drummer and swimming pool manager.
His novels are satirical, frequently farcical and offer a cynical view of contemporary Australian culture and its postcolonial and imperial foundations. Nine of his novels have been nominated for the Miles Franklin Award and he has won many other prestigious prizes for his novels and poetry. A double black-belt in tae kwon do, Foster is an avid reader of classical literature; an influence clearly discernible in the mythical and literary allusions that can be found in much of his work.
Foster is the father of Zoe Foster.