Lee Harding began writing stories when he was eight and purchased his first typewriter at twelve, determined to become a writer. However his first career was in photography, a profession he followed until 1969. Between 1971 and 1975 he worked as an assistant manager for Space Age Books, a Melbourne bookshop specialising in fantasy and science fiction. During this period he began writing for children and had a number of short science-fiction stories published in British and American magazines. He became a full-time writer in 1978.
Harding has edited several significant Australian science fiction anthologies, including Beyond Tomorrow (1975) and Rooms of Paradise (1978), and has written a number of science fiction novels for adults and children.
Harding has won awards for his books, as well as a number of writing fellowships from the Australia Council. Several of his stories and novels were adapted for radio broadcast in the late 1970s. Some of Harding's novels have been translated into German, Danish and Swedish.