George Miller is the son of Greek immigrant parents. He attended Ipswich Grammar School, then studied medicine at the University of New South Wales with his twin brother John. While in his final year at medical school, George and his younger brother Chris made a one-minute short film that won them first prize in a student competition. In 1971, George attended a film workshop at Melbourne University where he met fellow student, Byron Kennedy who would also become a film producer. Miller and Kennedy have collaborated on numerous works. In 1972, Miller completed his residency at Sydney's St Vincent's Hospital, spending his time off crewing on short experimental films.
Miller's first feature film as director was Mad Max , a film that won a variety of awards, including six Australian Film Institute (AFI) awards. Miller's role as producer of Flirting and Dead
Calm (films) and Bangkok Hilton and Vietnam (TV mini-series), all starring Nicole Kidman, was instrumental in the early development of her career.
In 2010, Miller became the first non United States of America citizen to be granted honorary membership of the Visual Effects Society for his long-standing contribution to the industry.