Van Ikin sold his first science fiction story at sixteen, and during his student days edited the fanzine Enigma for the Sydney University Science Fiction Association. Graduating with a PhD in English from the University of Sydney in 1980, he moved to Perth the same year to take up a position in the English Department at the University of Western Australia.
He has been a significant editorial influence on Australian science fiction. He has edited and published the journal Science Fiction: A Review of Speculative Literature since its inception in 1977, and his Australian Science Fiction (1981) was the first historical anthology of the genre. Following its publication he became a reviewer for the Sydney Morning Herald in 1984. He has worked as a freelance editor for a number of Australian publishers and has edited two major science fiction anthologies, in addition to being a co-author of the first book-length critical study of Australian Science Fiction (Strange Constellations, 1999).
Ikin has twice won the Australian Science Fiction Achievement Award for Best Editor, as well as the William Atheling Award for Criticism, and the A. Bertram Chandler Award for achievement in the field of science fiction (1992).
He is also a project leader in the Popular Fictions Research Community.