'Literature inspired by drugs tends to swing between extremes. On the one hand, drugs are the very doors of perception, gateways to Xanadu; on the other they are a source of grim addictions, lotus plants that tempt one into indefinite living sleep. In recent decades there have been the highs of William S. Burroughs, Tom Wolfe, Hunter S. Thompson and Irvine Welsh, but rarer are those memoirists with experiences of addiction and philosophy who can reflect on the subject in the tradition of Thomas De Quincey’s Confessions of an English Opium-Eater (1821). Well, cue Chris Fleming’s On Drugs.'(Introduction)